Preferential Selection of Low-Frequency, Lipopolysaccharide-Modified, Colistin-Resistant Mutants with a Combination of Antimicrobials in Acinetobacter baumannii

Author:

Kamoshida Go1ORCID,Yamada Noriteru1,Nakamura Tomoka1,Yamaguchi Daiki1,Kai Daichi1,Yamashita Maho1,Hayashi Chiaki1,Kanda Nana1,Sakaguchi Moe1,Morimoto Hitoshi1,Sawada Teppei1,Okada Tomoko1,Kaya Yuki1,Takemoto Norihiko2,Yahiro Kinnosuke1

Affiliation:

1. Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan

2. Pathogenic Microbe Laboratory, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Abstract

Acinetobacter baumannii has developed resistance to various antimicrobial drugs, and its drug-resistant strains cause nosocomial infections. Controlling these infections has become a global clinical challenge.

Funder

MEXT | Japan Society for the Promotion of Science

Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care

Kyoto Pharmaceutical University

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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