The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors-Reference-Cited by-同舟云学术

The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Berry Antoine¹²^ORCID,Menard Sandie¹,Nsango Sandrine E.³⁴,Abate Luc⁵,Concordet Didier⁶,Tchioffo Tsapi Majoline⁵,Iriart Xavier¹²,Awono-Ambéné Parfait H.⁷,Roche Benjamin⁵⁸⁹,Morlais Isabelle⁵

Affiliation:

1. Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse, CNRS UMR5051, INSERM UMR1291, UPS, Toulouse, France

2. Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Service de Parasitologie-Mycologie, Toulouse, France

3. Department of Biological Sciences, Faculté de Médecine et des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroon

4. Malaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon

5. MIVEGEC, IRD, CNRS, Université de Montpellier, Montpellier, France

6. INTHERES, Université de Toulouse, INRA, ENVT, Toulouse, France

7. Laboratoire d’Entomologie Médicale, Organisation de Coordination pour la Lutte contre les Endémies en Afrique Centrale, Yaoundé, Cameroon

8. International Center for Mathematical and Computational Modeling of Complex Systems (UMI IRD/UPMC UMMISCO), Bondy, France

9. Departamento de Etología, Fauna Silvestre y Animales de Laboratorio, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México

Abstract

Drug selection pressure in malaria patients is the cause of the emergence of resistant parasites. Resistance imposes a fitness cost for parasites in untreated infections, so withdrawal of the drug leads to the return of susceptible parasites.

Funder

Institut de medecine et Epidemiologie Applique

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00852-21

Reference45 articles.

1. Drug-resistant malaria: Molecular mechanisms and implications for public health

2. Antimalarial drug resistance