Impact of Molecular Syndromic Diagnosis of Severe Pneumonia in the Management of Critically Ill Patients-Reference-Cited by-同舟云学术

Impact of Molecular Syndromic Diagnosis of Severe Pneumonia in the Management of Critically Ill Patients

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Stafylaki Dimitra¹,Maraki Sofia¹,Vaporidi Katerina²,Georgopoulos Dimitrios²,Kontoyiannis Dimitrios P.³,Kofteridis Diamantis P.⁴,Chamilos Georgios¹^ORCID

Affiliation:

1. Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, Heraklion, Crete, Greece

2. ICU Department, University Hospital of Heraklion, Heraklion, Crete, Greece

3. Department of Infectious Diseases, The University of Texas, MD Anderson Cancer Center, Houston, Texas, USA

4. Internal Medicine Department, University Hospital of Heraklion, Heraklion, Crete, Greece

Abstract

The impact of syndromic molecular diagnosis in the management of nosocomial infections caused by MDR/XDR pathogens has been incompletely characterized. We evaluated the performance of a molecular syndromic platform (BioFire FilmArray -Pneumonia plus Panel) in 79 patients with pneumonia in the intensive care unit (ICU) of a University Hospital in Greece over a 2-year period (2018–2020) compared to 40 control patients diagnosed with pneumonia in the ICU the year before the study (2017–2018).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01616-22

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2. Attributable Mortality of Ventilator-Associated Pneumonia

3. Clinical Importance of Delays in the Initiation of Appropriate Antibiotic Treatment for Ventilator-Associated Pneumonia

4. Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia

5. Clinical epidemiology, treatment and prognostic factors of extensively drug-resistant Acinetobacter baumannii ventilator-associated pneumonia in critically ill patients

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