Interactions and Stability of Gut Microbiota in Zebrafish Increase with Host Development

Author:

Xiao Fanshu12,Zhu Wengen3,Yu Yuhe3,Huang Jie3,Li Juan24,He Zhili24,Wang Jianjun5,Yin Huaqun6ORCID,Yu Huang2,Liu Shengwei2,Chen Pubo2,Huang Zhijian2ORCID,He Jianguo2,Wang Cheng2,Shu Longfei2ORCID,Yan Qingyun2ORCID

Affiliation:

1. Center for Precision Medicine, Medical Research Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

2. Environmental Microbiomics Research Center, School of Environmental Science and Engineering, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), State Key Laboratory for Biocontrol, Sun Yat-sen University, Guangzhou, China

3. Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China

4. College of Agronomy, Hunan Agricultural University, Changsha, China

5. Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, China

6. School of Minerals Processing and Bioengineering, Central South University, Changsha, China

Abstract

Understanding gut microbial stability and the underlying mechanisms is an important but largely ignored ecological issue in vertebrate fish. Here, using a zebrafish model and network analysis of the gut microbiota we found that microbial interactions and stability in the gut ecosystem increase with fish development.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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