Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli-Reference-Cited by-同舟云学术

Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Du Gao-Fei¹^ORCID,Dong Yu²,Fan Xiaolu³,Yin Ankang¹,Le Yao-Jin⁴,Yang Xiao-Yan⁴^ORCID

Affiliation:

1. Key Laboratory of Laboratory Diagnostics, Medical Technology School, Xuzhou Medical University, Xuzhou, Jiangsu, China

2. Fujian Agriculture and Forestry University, Fuzhou, China

3. NHC Key Laboratory of Technical Evaluation of Fertility Regulation for Non-human Primate (Fujian Maternity and Child Health Hospital), Fuzhou, China

4. Department of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China

Abstract

CFDC was the first FDA-approved siderophore cephalosporin antibiotic in 2019 and is known for its Trojan horse tactics and broad antimicrobial activity against Gram-negative bacteria. However, its antibacterial mechanism is not fully understood, and whether it has an impact on in vivo iron ion homeostasis remains unknown.

Funder

Excellent Young Talents Fund Program of Zunyi Medical University

Outstanding Talents Research Start-up Foundation of Xuzhou Medical University

National Natural Science Foundation of China

Natural Science Foundation of Guizhou Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01093-22

Reference55 articles.

1. Global travel and Gram-negative bacterial resistance; implications on clinical management

2. Inhibiting the Evolution of Antibiotic Resistance

3. Emergence of Global Antibiotic Resistance

4. The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria

5. World health organization releases global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics

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