Bibliometric Review on New Possibilities of Antimycobacterial Agents: Exploring Siderophore Desferrioxamine’s Applications as an Antimicrobial Agent

Author:

de Oliveira Patrícia1,de Santana Lira Roseane2,de Abreu Lima Rafael2,Mendes Yasmim1,Martins Antenor3,de Melo Bruna4,Goiano Millena5,Filho Rivaldo6ORCID,de Farias Nunes Flávia7,Aliança Amanda13,Firmo Wellyson13ORCID,Carvalho Rafael2ORCID,Zagmignan Adrielle13ORCID,de Sousa Eduardo1234ORCID

Affiliation:

1. Graduate Program in Microbial Biology, CEUMA University—UNICEUMA, São Luís 65075-120, Brazil

2. Graduate Program in Health Sciences, Federal University of Maranhão—UFMA, São Luís 65080-805, Brazil

3. Graduate Program in Health and Services Management, CEUMA University—UNICEUMA, São Luís 65075-120, Brazil

4. Graduate Program in Biodiversity and Biotechnology—BIONORTE Amazonian Network, Federal University of Maranhão—UFMA, São Luís 65080-805, Brazil

5. Graduate Program in Biomedicine, CEUMA University—UNICEUMA, São Luís 65075-120, Brazil

6. Graduate Program in Nursing, St. Therese College—CEST, São Luís 65045-180, Brazil

7. Graduate Program in Nursing, Federal University of Maranhão—UFMA, São Luís 65080-805, Brazil

Abstract

Mycobacteria cause tuberculosis and other serious diseases. Understanding their mechanisms of resistance to our immune system and exploring novel drugs are critical strategies to combat infections. A bibliometric analysis was performed to identify publication trends and critical research areas in the field of the antimicrobial activity of desferrioxamine. A total of twenty-four publications on the topic, from 2012 to 2023, were retrieved from databases including Web of Science, Scopus, PubMed, and Embase, using specific keywords. The quality of the publications was assessed using impact and productivity metrics, with an average annual publication rate of 2.1 articles. The United States emerged as the most productive country, with medicine (23.4%, 11 publications) and biochemistry, genetics, and molecular biology (21.3%, 10 publications) as the top research fields. The five most cited publications accounted for 672 citations, with a relatively low h-index (11:11). In conclusion, there has been a lack of publications on this topic in the last decade. The United States dominates production and publication in this area, and there appears to be limited exchange of knowledge, ideas, and technology within the field. Therefore, fostering international cooperation through funding is essential to facilitate further research and development of desferrioxamine-related studies.

Funder

Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão

Publisher

MDPI AG

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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