Small Insertions and Deletions Drive Genomic Plasticity during Adaptive Evolution of Yersinia pestis

Author:

Wu Yarong1,Hao Tongyu12,Qian Xiuwei12,Zhang Xianglilan1,Song Yajun1ORCID,Yang Ruifu1,Cui Yujun1ORCID

Affiliation:

1. State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

2. School of Basic Medical Sciences, Anhui Medical University, Hefei, China

Abstract

Yersinia pestis, the causative agent of plague, is a highly pathogenic clone ofYersinia pseudotuberculosis. Previous genome-wide SNP analysis provided few adaptive signatures during its evolution.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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