Phenotypic Characterization and Heterogeneity among Modern Clinical Isolates of Acinetobacter baumannii

Author:

Valcek Adam12ORCID,Philippe Chantal3,Whiteway Clémence12,Robino Etienne12,Nesporova Kristina12ORCID,Bové Mona4,Coenye Tom4,De Pooter Tim56,De Coster Wouter78,Strazisar Mojca56,Van der Henst Charles12ORCID

Affiliation:

1. Microbial Resistance and Drug Discovery, VIB-VUB Center for Structural Biology, VIB, Flanders Institute for Biotechnology, Brussels, Belgium

2. Structural Biology Brussels, Vrije Universiteit Brussel (VUB), Brussels, Belgium

3. Research Unit in the Biology of Microorganisms (URBM), NARILIS, University of Namur (UNamur), Namur, Belgium

4. Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

5. Neuromics Support Facility, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium

6. Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium

7. Applied and Translational Neurogenomics Group, VIB Center for Molecular Neurology, VIB, Antwerp, Belgium

8. Applied and Translational Neurogenomics Group, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium

Abstract

Acinetobacter baumannii is a bacterium prioritized by the CDC and WHO because of its increasing antibiotic resistance, leading to treatment failures. The hallmark of this pathogen is the high heterogeneity observed among isolates, due to a very dynamic genome.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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