Screening Host Antiviral Proteins under the Enhanced Immune Responses Induced by a Variant Strain of Porcine Epidemic Diarrhea Virus-Reference-Cited by-同舟云学术

Screening Host Antiviral Proteins under the Enhanced Immune Responses Induced by a Variant Strain of Porcine Epidemic Diarrhea Virus

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Sun Min¹²³,Yu Zeyanqiu²⁴,Luo Miao²⁴,Li Bin¹^ORCID,Pan Zihao²⁴⁵,Ma Jiale²⁴⁵^ORCID,Yao Huochun²⁴⁵^ORCID

Affiliation:

1. Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China

2. College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China

3. School of Life Sciences, Jiangsu University, Zhenjiang, China

4. OIE Reference Lab for Swine Streptococcosis, Nanjing, China

5. Key Laboratory of Animal Bacteriology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, China

Abstract

Host innate immune responses, particularly interferon (IFN) antiviral signaling, can activate diverse downstream ISGs to exert antiviral effects. However, porcine epidemic diarrhea virus (PEDV) infection has evolved multiple strategies to escape from this immune clearance.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00661-22

Reference44 articles.

1. Virus-like particles associated with porcine epidemic diarrhoea