Cyclosporine A Inhibits Viral Infection and Release as Well as Cytokine Production in Lung Cells by Three SARS-CoV-2 Variants-Reference-Cited by-同舟云学术

Cyclosporine A Inhibits Viral Infection and Release as Well as Cytokine Production in Lung Cells by Three SARS-CoV-2 Variants

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Fenizia Claudio¹²,Galbiati Silvia³,Vanetti Claudia¹²,Vago Riccardo⁴⁵,Clerici Mario¹⁶,Tacchetti Carlo⁵⁷,Daniele Tiziana⁷^ORCID

Affiliation:

1. Department of Pathophysiology and Transplantation, Milano University Medical School, Milan, Italy

2. Department of Biomedical and Clinical Sciences “L Sacco,” Milano University Medical School, Milan, Italy

3. Complication of Diabetes Unit, Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy

4. Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy

5. Vita-Salute San Raffaele University, Milan, Italy

6. IRCCS Don Carlo Gnocchi Foundation, Milan, Italy

7. Cancer Imaging Unit, Experimental Imaging Centre, IRCCS San Raffaele Scientific Institute, Milan, Italy

Abstract

SARS-CoV-2 is the most recently identified member of the betacoronavirus genus responsible for the COVID-19 pandemic. Repurposing of available drugs has been a “quick and dirty” approach to try to reduce mortality and severe symptoms in affected patients initially, and can still represent an undeniable and valuable approach to face COVID-19 as the continuous appearance and rapid diffusion of more “aggressive”/transmissible variants, capable of eluding antibody neutralization, challenges the effectiveness of some anti-SARS-CoV-2 vaccines.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01504-21

Reference88 articles.

1. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

2. Clinical Characteristics of Coronavirus Disease 2019 in China

3. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

4. The cytokine storm and COVID‐19

5. Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes

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