Transcriptomic Analysis of Vibrio parahaemolyticus Underlying the Wrinkly and Smooth Phenotypes-Reference-Cited by-同舟云学术

Transcriptomic Analysis of Vibrio parahaemolyticus Underlying the Wrinkly and Smooth Phenotypes

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wu Qimin¹,Li Xue¹,Zhang Tingting¹,Zhang Miaomiao²,Xue Xingfan²,Yang Wenhui³,Hu Lingfei³,Yin Zhe³,Zhou Dongsheng³^ORCID,Sun Yuyu¹,Lu Renfei¹,Zhang Yiquan¹^ORCID

Affiliation:

1. Department of Clinical Laboratory, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China

2. School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China

3. State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

Abstract

We showed that Vibrio parahaemolyticus was able to naturally and reversibly switch between wrinkly and smooth phenotypes and disclosed the gene expression profiles related to wrinkly-smooth switching, showing that the significantly differentially expressed genes between the two colony morphology phenotypes were involved in various biological behaviors, including virulence factor production, biofilm formation, metabolism, adaptation, and colonization.

Funder

National Natural Science Foundation of China

Natural Science Research Project of Nantong Science and Technology Bureau

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02188-22

Reference83 articles.

1. Vibrio parahaemolyticus cell biology and pathogenicity determinants

2. Molecular mechanisms of Vibrio parahaemolyticus pathogenesis