Comparative Analysis of Phylogenetic Relationships and Virulence Factor Characteristics between Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolates Derived from Clinical Sites and Chicken Farms

Author:

Li Chao12ORCID,Chen Xuan12,Ju Zijing12,Li Cui12,Xu Ying3,Ding Jiawei4,Wang Yuting12,Ma Peng12,Gu Kui12,Lei Changwei12,Tang Yizhi12ORCID,Wang Hongning12ORCID

Affiliation:

1. Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China

2. Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan, China

3. The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China

4. Clinical Laboratory Department, Yan’an Hospital Affiliated with Kunming Medical University, Kunming, Yunnan, China

Abstract

Bacterial drug resistance has become one of the most significant threats to human health worldwide, especially for extended-spectrum β-lactamase-producing E. coli (ESBL- E. coli ). Timely and accurate epidemiological surveys can provide scientific guidance for the adoption of treatments in different regions and also reduce the formation of drug-resistant bacteria.

Funder

The National System for Layer Production Technology

Foundation for Innovative Research Groups of the National Natural Science Foundation of China

MOE | Fundamental Research Funds for the Central Universities

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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