Variants of Tn 6924 , a Novel Tn 7 Family Transposon Carrying the bla NDM Metallo-β-Lactamase and 14 Copies of the aphA6 Amikacin Resistance Genes Found in Acinetobacter baumannii

Author:

Mann Riti1,Rafei Rayane2,Gunawan Cindy13,Harmer Christopher J.4ORCID,Hamidian Mohammad1ORCID

Affiliation:

1. The iThree Institute, University of Technology Sydney, Ultimo, New South Wales, Australia

2. Laboratoire Microbiologie Santé et Environnement (LMSE), Doctoral School of Science & Technology, Faculty of Public Health, Lebanese University, Tripoli, Lebanon

3. School of Chemical Engineering, University of New South Wales, Sydney, New South Wales, Australia

4. School of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia

Abstract

To date, efforts to study the resistance mechanisms of carbapenem-resistant Acinetobacter baumannii have been largely focused on the two major globally distributed clones (GC1 and GC2). ST85 is an emerging sequence type, and unlike other clones, it is associated with the carriage of the bla NDM gene.

Funder

Australian Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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