High Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Isolates Recovered in Nigerian Hospitals in 2016 to 2020-Reference-Cited by-同舟云学术

High Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Isolates Recovered in Nigerian Hospitals in 2016 to 2020

Published:2023-06-22 Issue:3 Volume:8 Page:
ISSN:2379-5042
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language:en
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Author:

Odih Erkison Ewomazino¹²^ORCID,Oaikhena Anderson O.¹,Underwood Anthony³,Hounmanou Yaovi Mahuton Gildas²^ORCID,Oduyebo Oyinlola O.⁴,Fadeyi Abayomi⁵,Aboderin Aaron O.⁶,Ogunleye Veronica O.⁷,Argimón Silvia³,Akpunonu Vitus Nnaemeka⁸,Oshun Phillip O.⁴,Egwuenu Abiodun⁹,Okwor Tochi J.⁹,Ihekweazu Chikwe⁹,Aanensen David M.³,Dalsgaard Anders²,Okeke Iruka N.¹^ORCID

Affiliation:

1. Global Health Research Unit for the Genomic Surveillance of Antimicrobial Resistance, Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ibadan, Ibadan, Oyo State, Nigeria

2. Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

3. Centre for Genomic pathogen Surveillance, Big Data Institute, University of Oxford, Oxford, United Kingdom

4. Department of Medical Microbiology and Parasitology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Nigeria

5. Department of Medical Microbiology and Parasitology, University of Ilorin, Ilorin, Kwara State, Nigeria

6. Department of Medical Microbiology and Parasitology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria

7. Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria

8. Clina-Lancet Laboratories, Victoria Island, Lagos State, Nigeria

9. Nigeria Centre for Disease Control, Abuja, Nigeria

Abstract

Acinetobacter baumannii bacteria are increasingly clinically relevant due to their propensity to harbor genes conferring resistance to multiple antimicrobials, as well as their ability to persist and disseminate in hospital environments and cause difficult-to-treat nosocomial infections. Little is known about the molecular epidemiology and antimicrobial resistance profiles of these organisms in Nigeria, largely due to limited capacity for their isolation, identification, and antimicrobial susceptibility testing.

Funder

Official Development Assistance (ODA) funding from the National Institute of Health Research

National Institute of Health Research using Official Development Assistance (ODA) Funding

University of Copenhagen

Department of Health and Social Care's Fleming Fund using UK aid.

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00098-23