Parallel Evolution of Pseudomonas aeruginosa during a Prolonged ICU-Infection Outbreak

Author:

Cameron David R.1,Pitton Melissa12,Oberhaensli Simone3,Schlegel Katja4,Prod’hom Guy5,Blanc Dominique S.6,Jakob Stephan M.1,Que Yok-Ai1ORCID

Affiliation:

1. Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

2. Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland

3. Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland

4. Institute of Psychology, University of Bern, Bern, Switzerland

5. Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

6. Service of Hospital Preventive Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

Abstract

Pseudomonas aeruginosa is a Gram-negative pathogen causing infections in acutely burned patients. The precise mechanisms required for the establishment of infection in the burn setting, and adaptive traits underpinning prolonged outbreaks are not known.

Funder

Stiftung fuer Anesthaesiologie and Intensivemedizin

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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