Development of a Universal Cloning System for Reverse Genetics of Human Enteroviruses-Reference-Cited by-同舟云学术

Development of a Universal Cloning System for Reverse Genetics of Human Enteroviruses

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Choi Won-Suk¹²^ORCID,Oh Sol¹,Antigua Khristine Joy C.³,Jeong Ju Hwan¹^ORCID,Kim Beom Kyu¹,Yun Yu Soo¹,Kang Da Hyeon¹,Min Seong Cheol¹,Lim Byung-Kwan⁴,Kim Won Seop⁵,Lee Ji-Hyuk⁵,Kim Eung-Gook⁶,Choi Young Ki¹⁷^ORCID,Baek Yun Hee¹,Song Min-Suk¹²^ORCID

Affiliation:

1. Department of Microbiology, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Chungbuk, Republic of Korea

2. Microuni Co., Ltd., Cheongju, Chungbuk, Republic of Korea

3. Animal Health and Welfare Division, Bureau of Animal Industry (BAI), Department of Agriculture (DA), Quezon City, Philippines

4. Department of Biomedical Science, Jungwon University, Goesan-gun, Chungbuk, Republic of Korea

5. Department of Pediatrics, College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea

6. Department of Biochemistry, Chungbuk National University College of Medicine and Medical Research Institute, Cheongju, Chungbuk, Republic of Korea

7. Center for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science (IBS), Daejeon, Republic of Korea

Abstract

Due to the broad spread, incidence, and genetic divergence of enteroviruses (EVs), it has been challenging to deal with this virus that causes severe human diseases, including aseptic meningitis, myocarditis, encephalitis, and poliomyelitis. Therefore, an efficient and universal cloning system for the reverse genetics of highly divergent EVs contributes to an understanding of the viral pathology and molecular mechanisms of evolution.

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03167-22

Reference35 articles.

1. Picornaviridae: The Enteroviruses (Polioviruses, Coxsackieviruses, Echoviruses)

2. Poliovirus and Other Enteroviruses

3. Molecular Pathogenicity of Enteroviruses Causing Neurological Disease

4. Enterovirus and Encephalitis

5. The epidemiology of non-polio enteroviruses

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