Combined Prospective Seroconversion and PCR Data of Selected Cohorts Indicate a High Rate of Subclinical SARS-CoV-2 Infections—an Open Observational Study in Lower Saxony, Germany-Reference-Cited by-同舟云学术

Combined Prospective Seroconversion and PCR Data of Selected Cohorts Indicate a High Rate of Subclinical SARS-CoV-2 Infections—an Open Observational Study in Lower Saxony, Germany

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Jonczyk Rebecca¹,Stanislawski Nils²,Seiler Lisa K.¹,Blume Holger²,Heiden Stefanie³,Lucas Henning³,Sarikouch Samir⁴,Pott Philipp-Cornelius⁵,Stiesch Meike⁵,Hauß Corinna⁶,Saletti Giulietta⁷,González-Hernández Mariana⁷,Kaiser Franziska Karola⁷,Rimmelzwaan Guus⁷,Osterhaus Albert⁷,Blume Cornelia¹^ORCID

Affiliation:

1. Institute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany

2. Institute of Microelectronic Systems, Leibniz University Hannover, Hannover, Germany

3. Institute of Innovation Research, Technology Management & Entrepreneurship, Leibniz University Hannover, Hannover, Germany

4. Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany

5. Clinic for Dental Prosthetics and Biomedical Materials Science, Hannover Medical School, Hannover, Germany

6. MVZ Labor Limbach Hannover GbR, Lehrte, Germany

7. Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Foundation, Hannover, Germany

Abstract

Within this open observational study, repeated PCR ( n > 4,700) and antibody screening ( n > 1,600) tests were offered in three different working fields. The study identified 51 subjects with acute SARS-CoV-2 infection and 37 subjects reported to have had a positive PCR test taken externally.

Funder

Ministry of Economics Lower Saxony, Germany

Ministry of Education, Lower Saxony, Germany

Minstry of Economics, Lower Saxony, Germany

Alexander von Humboldt-Stiftung

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01512-21

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