Modular Inducible Multigene Expression System for Filamentous Fungi

Author:

Baldin Clara1,Kühbacher Alexander1,Merschak Petra1,Wagener Johannes2ORCID,Gsaller Fabio1ORCID

Affiliation:

1. Institute of Molecular Biology, Biocenter Innsbruck, Medical University of Innsbruck, Innsbruck, Austria

2. Department of Clinical Microbiology, School of Medicine, Trinity College Dublin, The University of Dublin, Dublin, Ireland

Abstract

In recent years, inducible promoters have gained increasing interest for industrial or laboratory use and have become key instruments for protein expression, synthetic biology, and metabolic engineering. Constitutive, high-expressing promoters can be used to achieve high expression yields; however, the continuous overexpression of specific proteins can lead to an unpredictable metabolic burden.

Funder

Austrian Science Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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