Horizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness-Reference-Cited by-同舟云学术

Horizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Krauss Sophia¹²³,Harbig Theresa A.⁴,Rapp Johanna²⁵,Schaefle Timm²⁶,Franz-Wachtel Mirita⁷,Reetz Leonie¹²³,Elsherbini Ahmed M. A.¹²³,Macek Boris⁷,Grond Stephanie²⁶,Link Hannes²⁵,Nieselt Kay⁴,Krismer Bernhard¹²³^ORCID,Peschel Andreas¹²³^ORCID,Heilbronner Simon²³⁸^ORCID

Affiliation:

1. Department of Infection Biology, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany

2. Cluster of Excellence EXC 2124, Controlling Microbes to Fight Infections, Tübingen, Germany

3. German Center for Infection Research, Tübingen, Germany

4. Interfaculty Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany

5. Department of Bacterial Metabolomics, Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany

6. Institute of Organic Chemistry, University of Tübingen, Tübingen, Germany

7. Proteome Center Tübingen, University of Tübingen, Tübingen, Germany

8. Interfaculty Institute of Microbiology and Infection Medicine, Institute for Medical Microbiology and Hygiene, UKT Tübingen, Tübingen, Germany

Abstract

Human microbiomes are critically associated with human health and disease. Importantly, pathogenic bacteria can hide in human-associated communities and can cause disease when the composition of the community becomes unbalanced.

Funder

Deutsche Forschungsgemeinschaft

Deutsches Zentrum für Infektionsforschung

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03176-22

Reference84 articles.

1. The microbiome-shaping roles of bacteriocins

2. Bacteriocins — a viable alternative to antibiotics?