Reevaluating Rifampicin Breakpoint Concentrations for Mycobacterium tuberculosis Isolates with Disputed <i>rpoB</i> Mutations and Discordant Susceptibility Phenotypes-Reference-Cited by-同舟云学术

Reevaluating Rifampicin Breakpoint Concentrations for Mycobacterium tuberculosis Isolates with Disputed rpoB Mutations and Discordant Susceptibility Phenotypes

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Wei¹,Liu Rongmei²,Yao Cong¹,Huo Fengmin³,Shang Yuanyuan¹,Zhang Xuxia¹,Wang Yufeng⁴,Xue Zhongtan¹,Ma Liping²,Pang Yu¹^ORCID

Affiliation:

1. Department of Bacteriology and Immunology, Beijing Key Laboratory on Drug-Resistant Tuberculosis Research, Beijing Tuberculosis and Thoracic Tumor Research Institute/Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China

2. Department of Tuberculosis, Beijing Tuberculosis and Thoracic Tumor Research Institute/Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China

3. National Tuberculosis Clinical Laboratory, Beijing Tuberculosis and Thoracic Tumor Research Institute/Beijing Chest Hospital, Capital Medical University, Beijing, People’s Republic of China

4. Innovation Alliance on Tuberculosis Diagnosis and Treatment, Beijing, People’s Republic of China

Abstract

Tuberculosis (TB) is still one of the world's leading infectious disease killers. The early and accurate diagnosis of RIF resistance is necessary to deliver timely and appropriate treatment for TB patients and improve their clinical outcome.

Funder

Beijing Hospital Authority

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02087-21

Reference26 articles.

1. World Health Organization. 2021. WHO global tuberculosis report 2021. World Health Organization, Geneva, Switzerland.

2. MDR Tuberculosis — Critical Steps for Prevention and Control

3. Optimization of the Rifampin Dosage to Improve the Therapeutic Efficacy in Tuberculosis Treatment Using a Murine Model

4. Study of the Rifampin Monoresistance Mechanism in Mycobacterium tuberculosis

5. World Health Organization. 2020. WHO consolidated guidelines on tuberculosis, module 4: treatment - drug-resistant tuberculosis treatment. World Health Organization, Geneva, Switzerland.

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