In Vitro Activity of KBP-7072 against 536 Acinetobacter baumannii Complex Isolates Collected in China

Author:

Han Renru12,Ding Li12,Yang Yang12,Guo Yan12,Yin Dandan12,Wu Shi12,Zhi Peiyuan12,Zhu Demei12,Liu Qingmei3,Tan Xiaojuan3,Zhu Yuanju3,Zhang Jay4,Li Li3,Hu Fupin12ORCID

Affiliation:

1. Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China

2. Key Laboratory of Clinical Pharmacology of Antibiotics, Ministry of Health, Shanghai, China

3. KBP Biosciences Co. Ltd., Jinan, Shandong, China

4. KBP Biosciences USA Inc., Princeton, New Jersey, USA

Abstract

It is reported that A. baumannii has emerged as an intractable nosocomial pathogen in hospitals especially when it develops resistance to carbapenems and other antibiotics, which limits treatment options and leads to high mortality. In February 2017, the WHO published a list of ESKAPE pathogens designated “priority status” for which new antibiotics are urgently needed.

Funder

National Mega-project for Innovative Drugs

China Antimicrobial Surveillance

Science and Technology Innovation Action Plan of Shanghai Science and Technology Committee

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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