Phage Cocktail Targeting STEC O157:H7 Has Comparable Efficacy and Superior Recovery Compared with Enrofloxacin in an Enteric Murine Model-Reference-Cited by-同舟云学术

Phage Cocktail Targeting STEC O157:H7 Has Comparable Efficacy and Superior Recovery Compared with Enrofloxacin in an Enteric Murine Model

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Yuxin¹,Subedi Dinesh²^ORCID,Li Jin¹,Wu Jiaoling¹,Ren Jianluan¹,Xue Feng¹,Dai Jianjun¹³,Barr Jeremy J.²^ORCID,Tang Fang¹^ORCID

Affiliation:

1. MOE Joint International Research Laboratory of Animal Health and Food Safety; Key Laboratory of Animal Bacteriology, Ministry of Agriculture; and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China

2. School of Biological Sciences, Monash University, Victoria, Australia

3. School of Life Science and Technology, China Pharmaceutical University, Nanjing, China

Abstract

With the increasing severity of antibiotic resistance and other adverse consequences, animal experiments and clinical trials investigating the use of phages for the control and prevention of enteric bacterial infections are growing. However, the effects of phages and antibiotics on organisms when treating intestinal infections have not been precisely studied.

Funder

National Natural Science Foundation of China

The Fund of Priority Academic Program Development of Jiangsu Higher Education Insititutions

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00232-22

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