Affiliation:
1. Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft, 31535 Neustadt-Mariensee, Germany
Abstract
ABSTRACT
The
Staphylococcus lentus
plasmid pSCFS2 carries a novel florfenicol-chloramphenicol resistance gene, designated
fexA
, encoding a protein of 475 amino acids with 14 transmembrane domains. The FexA protein differs from all previously known proteins involved in the efflux of chloramphenicol and florfenicol. Induction of
fexA
expression by chloramphenicol and florfenicol occurs via translational attenuation.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
108 articles.
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