Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections-Reference-Cited by-同舟云学术

Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections

Published:2022-08-16 Issue:8 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Souche Aubin¹²,Kolenda Camille¹²,Teoli Jordan³,Schuch Raymond⁴^ORCID,Ferry Tristan¹³⁵⁶,Laurent Frédéric¹²³⁵,Josse Jérôme¹³⁵^ORCID

Affiliation:

1. CIRI–Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France

2. Laboratoire de Bactériologie, Institut des Agents Infectieux, Hospices Civils de Lyon, Lyon, France

3. Université Claude Bernard Lyon 1, Lyon, France

4. ContraFect Corporation, Yonkers, New York, USA

5. Centre de Référence des Infections Ostéo-articulaires Complexes (CRIOAc Lyon), Hospices Civils de Lyon, Lyon, France

6. Service des Maladies Infectieuses, Hospices Civils de Lyon, Lyon, France

Abstract

Staphylococcus epidermidis is one of the main pathogens responsible for bone and joint infections, especially those involving prosthetic materials, due to its ability to form biofilms. In these cases, biofilm formation, combined with increased antimicrobial resistance, often results in therapeutic failures.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00588-22

Reference54 articles.

1. Key features of bone and joint infections following the implementation of reference centers in France

2. Bone and joint infections in hospitalized patients in France, 2008: clinical and economic outcomes

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