Clostridium perfringens Enterotoxin Damages the Human Intestine In Vitro-Reference-Cited by-同舟云学术

Clostridium perfringens Enterotoxin Damages the Human Intestine In Vitro

Published:2005-12 Issue:12 Volume:73 Page:8407-8410
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Fernández Miyakawa M. E.¹,Pistone Creydt V.²,Uzal F. A.¹,McClane B. A.³,Ibarra C.²

Affiliation:

1. California Animal Health and Food Safety Laboratory, University of California—Davis, San Bernardino, California

2. Laboratorio de Fisiopatogenia, Departamento de Fisiología, Universidad de Buenos Aires, Buenos Aires, Argentina

3. Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Abstract

ABSTRACT In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport changes that are not statistically significant.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.73.12.8407-8410.2005

Reference26 articles.

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4. Death Pathways Activated in CaCo-2 Cells by Clostridium perfringens Enterotoxin

5. Dorr, R. A., A. Kierbel, J. Vera, and M. Parisi. 1997. A new data-acquisition system for the measurement of the net water flux across epithelia. Comput. Methods Programs Biomed.53:9-14.

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