Azurin of Pathogenic Neisseria spp. Is Involved in Defense against Hydrogen Peroxide and Survival within Cervical Epithelial Cells-Reference-Cited by-同舟云学术

Azurin of Pathogenic Neisseria spp. Is Involved in Defense against Hydrogen Peroxide and Survival within Cervical Epithelial Cells

Published:2005-12 Issue:12 Volume:73 Page:8444-8448
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wu Hsing-Ju¹,Seib Kate L.¹,Edwards Jennifer L.²,Apicella Michael A.²,McEwan Alastair G.¹,Jennings Michael P.¹

Affiliation:

1. The School of Molecular and Microbial Sciences and Centre for Metals in Biology, The University of Queensland, Brisbane 4072, Australia

2. Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa 52242

Abstract

ABSTRACT Laz, a lipid-modified azurin of the human pathogens Neisseria gonorrhoeae and Neisseria meningitidis , is involved in defense against oxidative stress and copper toxicity; laz mutant strains are hypersensitive to hydrogen peroxide and copper. The N. gonorrhoeae laz mutant also has decreased survival in an ex vivo primary human ectocervical epithelial assay.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.73.12.8444-8448.2005

Reference36 articles.

1. Alexander, H. E. 1965. The Haemophilus group, p. 724-741. In R. J. Dubos and J. G. Hirsch (ed.), Bacterial and mycotic infection in man. Pitman Medical Publishing, London, United Kingdom.

2. Apicella, M. A., M. Ketterer, F. K. Lee, D. Zhou, P. A. Rice, and M. S. Blake. 1996. The pathogenesis of gonococcal urethritis in men: confocal and immunoelectron microscopic analysis of urethral exudates from men infected with Neisseria gonorrhoeae. J. Infect. Dis.173:636-646.

3. Increased Expression of Periplasmic Cu,Zn Superoxide Dismutase Enhances Survival of Escherichia coli Invasive Strains within Nonphagocytic Cells

4. Cannon, J. G. 1989. Conserved lipoproteins of pathogenic Neisseria species bearing the H.8 epitope: lipid-modified azurin and H.8 outer membrane protein. Clin. Microbiol. Rev.2(Suppl.):S1-S4.

5. Cohen, M. S., J. G. Cannon, A. E. Jerse, L. M. Charniga, S. F. Isbey, and L. G. Whicker. 1994. Human experimentation with Neisseria gonorrhoeae: rationale, methods, and implications for the biology of infection and vaccine development. J. Infect. Dis.169:532-537.

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population;Nature Communications;2024-08-07

2. BacA: a possible regulator that contributes to the biofilm formation of Pseudomonas aeruginosa;Frontiers in Microbiology;2024-03-05

3. Cold-Azurin, a New Antibiofilm Protein Produced by the Antarctic Marine Bacterium Pseudomonas sp. TAE6080;Marine Drugs;2024-01-25

4. Defeat undefeatable: Ionic liquids as novel antimicrobial agents;Journal of Molecular Liquids;2023-01

5. The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron;PLOS Pathogens;2022-06-17