Clinical and Bacteriologic Analysis of Nontypeable Haemophilus influenzae Strains Isolated from Children with Invasive Diseases in Japan from 2008 to 2015

Author:

Naito Sachiko1,Takeuchi Noriko2,Ohkusu Misako2,Takahashi-Nakaguchi Azusa2,Takahashi Hiroki2,Imuta Naoko3,Nishi Junichiro3,Shibayama Keigo4,Matsuoka Mayumi4,Sasaki Yuko4,Ishiwada Naruhiko2

Affiliation:

1. Chiba University Graduate School of Medicine, Chiba, Japan

2. Medical Mycology Research Center, Chiba University, Chiba, Japan

3. Department of Microbiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

4. Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan

Abstract

Haemophilus influenzae type b (Hib) conjugate vaccines have led to dramatic reductions in Hib disease among young children worldwide. Nontypeable H. influenzae (NTHi) is now the major cause of invasive H. influenzae infections.

Funder

Japanese Ministry of Health and Labor, and Welfare

Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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