Interaction between Posaconazole and Caspofungin in Concomitant Treatment of Mice with Systemic Aspergillus Infection-Reference-Cited by-同舟云学术

Interaction between Posaconazole and Caspofungin in Concomitant Treatment of Mice with Systemic Aspergillus Infection

Published:2006-07 Issue:7 Volume:50 Page:2587-2590
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Cacciapuoti Anthony¹,Halpern Judith¹,Mendrick Cara¹,Norris Christine¹,Patel Reena¹,Loebenberg David¹

Affiliation:

1. Schering-Plough Research Institute, Kenilworth, New Jersey

Abstract

ABSTRACT The interaction of posaconazole and caspofungin was evaluated in concomitant treatment of Aspergillus fumigatus (two strains) or A. flavus (one strain) systemic infections in immunocompetent mice. Survival curves for mice treated with the combinations were compared statistically with those for mice treated with the component monotherapies. No antagonism was observed.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00829-05

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