Presence of the KPC Carbapenemase Gene in Enterobacteriaceae Causing Bacteremia and Its Correlation with In Vitro Carbapenem Susceptibility-Reference-Cited by-同舟云学术

Presence of the KPC Carbapenemase Gene in Enterobacteriaceae Causing Bacteremia and Its Correlation with In Vitro Carbapenem Susceptibility

Published:2009-01 Issue:1 Volume:47 Page:239-241
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Marschall Jonas¹,Tibbetts Robert J.²,Dunne W. Michael²,Frye Jonathan G.³,Fraser Victoria J.¹,Warren David K.¹

Affiliation:

1. Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri

2. Medical Microbiology, Division of Laboratory Medicine, Washington University School of Medicine, St. Louis, Missouri

3. Bacterial Epidemiology and Antimicrobial Resistance Research Unit, USDA, Agricultural Research Service, Athens, Georgia

Abstract

ABSTRACT During 6 months, we obtained Enterobacteriaceae isolates from patients with gram-negative bacteremia at a 1,250-bed teaching hospital in St. Louis, MO, and compared carbapenem susceptibilities with the presence of bla KPC , a transferable carbapenemase gene. Three (1.2%) out of 243 isolates were bla KPC positive. Ertapenem nonsusceptibility had a low positive predictive value.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02123-08

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