Emergence of KPC-Possessing Klebsiella pneumoniae in Brooklyn, New York: Epidemiology and Recommendations for Detection-Reference-Cited by-同舟云学术

Emergence of KPC-Possessing Klebsiella pneumoniae in Brooklyn, New York: Epidemiology and Recommendations for Detection

Published:2005-07 Issue:7 Volume:49 Page:3018-3020
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Bratu Simona¹,Mooty Mohamad¹,Nichani Satyen¹,Landman David¹,Gullans Carl²,Pettinato Barbara³,Karumudi Usha¹,Tolaney Pooja¹,Quale John¹

Affiliation:

1. Department of Medicine, SUNY-Downstate Medical Center

2. Department of Microbiology, Kings County Hospital

3. Department of Pathology Services, Coney Island Hospital, Brooklyn, New York

Abstract

ABSTRACT Among 257 isolates of Klebsiella pneumoniae collected in Brooklyn, NY, 24% were found to possess bla KPC . Clinical microbiology laboratories that used automated broth microdilution systems reported 15% of the KPC-possessing isolates as susceptible to imipenem. The imipenem MIC was found to be markedly affected by the inoculum. For accurate detection of KPC-possessing K. pneumoniae , particular attention should be paid to proper inoculum preparation for broth-based susceptibility methods. In addition, using ertapenem or meropenem for class reporting of carbapenem susceptibility will improve detection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.7.3018-3020.2005

Reference9 articles.

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