Plasmid-Mediated Carbapenem-Hydrolyzing Enzyme KPC-2 in an Enterobacter sp-Reference-Cited by-同舟云学术

Plasmid-Mediated Carbapenem-Hydrolyzing Enzyme KPC-2 in an Enterobacter sp

Published:2004-11 Issue:11 Volume:48 Page:4438-4440
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hossain Ashfaque¹²,Ferraro M. J.³,Pino R. M.³,Dew R. B.³,Moland E. S.¹²,Lockhart T. J.¹²,Thomson K. S.¹²,Goering R. V.²,Hanson N. D.¹²

Affiliation:

1. Center for Research in Anti-Infectives and Biotechnology

2. Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska

3. Massachusetts General Hospital, Boston, Massachusetts

Abstract

ABSTRACT A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 β-lactamase, was isolated from a patient with sepsis at a Boston hospital. This is the first report of the production of a plasmid-encoded KPC-2 β-lactamase by an Enterobacter sp.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.11.4438-4440.2004

Reference12 articles.

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