Type II Fatty Acid Synthesis Pathway and Cyclopropane Ring Formation Are Dispensable during Enterococcus faecalis Systemic Infection-Reference-Cited by-同舟云学术

Type II Fatty Acid Synthesis Pathway and Cyclopropane Ring Formation Are Dispensable during Enterococcus faecalis Systemic Infection

Published:2021-09-23 Issue:20 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Hays Constantin¹²³,Lambert Clara¹,Brinster Sophie¹,Lamberet Gilles⁴,du Merle Laurence⁵⁶,Gloux Karine⁴,Gruss Alexandra⁴^ORCID,Poyart Claire¹²³,Fouet Agnes¹²^ORCID

Affiliation:

1. Université de Paris, Institut Cochin, INSERM, CNRS, Paris, France

2. Centre National de Référence des Streptocoques, Paris, France

3. Hôpitaux Universitaires Paris Centre, Site Cochin, Assistance Publique Hôpitaux de Paris, Paris, France

4. MICALIS, UMR1319, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement, Domaine de Vilvert, Jouy en Josas, France

5. Institut Pasteur, Unité de Biologie des Bactéries Pathogènes à Gram Positif, Paris, France

6. CNRS ERL3526, Paris, France

Abstract

Membrane lipid homeostasis is crucial for bacterial physiology, adaptation, and virulence. Fatty acids are constituents of the phospholipids that are essential membrane components.

Funder

Agence Nationale de la Recherche

Fondation pour la Recherche Médicale

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00221-21

Reference47 articles.

1. Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

2. Isolation and Characterization of Unsaturated Fatty Acid Auxotrophs of Streptococcus pneumoniae and Streptococcus mutans