Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/nature07772.pdf
Reference31 articles.
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2. Marrakchi, H., Zhang, Y. M. & Rock, C. O. Mechanistic diversity and regulation of Type II fatty acid synthesis. Biochem. Soc. Trans. 30, 1050–1055 (2002)
3. Price, A. C. et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J. Biol. Chem. 276, 6551–6559 (2001)
4. Wright, H. T. & Reynolds, K. A. Antibacterial targets in fatty acid biosynthesis. Curr. Opin. Microbiol. 10, 447–453 (2007)
5. Zhang, Y. M., White, S. W. & Rock, C. O. Inhibiting bacterial fatty acid synthesis. J. Biol. Chem. 281, 17541–17544 (2006)
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