Characterization of Functional B-Cell Epitopes at the Amino Terminus of <i>Shigella</i> Invasion Plasmid Antigen B (IpaB)-Reference-Cited by-同舟云学术

Characterization of Functional B-Cell Epitopes at the Amino Terminus of Shigella Invasion Plasmid Antigen B (IpaB)

Published:2022-08-09 Issue:15 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Li Siqi¹,Han Xinfeng¹²,Upadhyay Ipshita¹,Zhang Weiping¹^ORCID

Affiliation:

1. Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

2. Sichuan Agricultural University College of Veterinary Medicine, Chengdu, Sichuan, People’s Republic of China

Abstract

Currently, there are no effective measures for control or prevention of Shigella infection, the most common cause of diarrhea in children 3 to 5 years of age in developing countries. Challenges in developing Shigella vaccines include virulence heterogeneity among species and serotypes.

Funder

HHS | National Institutes of Health

UofI | University of Illinois at Urbana-Champaign

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00384-22

Reference49 articles.

1. Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016

2. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study