Affiliation:
1. Department of Microbiology, Wayne State University School of Medicine, Detroit, Michigan 48201
Abstract
A bacteriphage typing scheme for differentiating
Proteus
isolated from clinical specimens was developed. Twenty-one distinct patterns of lysis were seen when 15 bacteriophages isolated on 8
Proteus mirabilis
, 1
P. vulgaris
, and 1
P. morganii
were used to type 162 of 189 (85.7%)
P. mirabilis
and
P. vulgaris
isolates. Seven phages isolated on 3
P. morganii
were used to type 13 of 19 (68.4%)
P. morganii
isolates. Overall, 84.1% of the 208 isolates were lysed by at least 1 phage at routine test dilution (RTD) or 1,000 × RTD. Fifty isolates, retyped several weeks after the initial testing, showed no changes in lytic patterns. The phages retained their titers after storage at 4 C for several months. A computer analysis of the data showed that there was no relationship between the source of the isolate and bacteriophage type. This bacteriophage typing system may provide epidemiological information on strains involved in human infections.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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