Scaffolding Protein GspB/OutB Facilitates Assembly of the Dickeya dadantii Type 2 Secretion System by Anchoring the Outer Membrane Secretin Pore to the Inner Membrane and to the Peptidoglycan Cell Wall-Reference-Cited by-同舟云学术

Scaffolding Protein GspB/OutB Facilitates Assembly of the Dickeya dadantii Type 2 Secretion System by Anchoring the Outer Membrane Secretin Pore to the Inner Membrane and to the Peptidoglycan Cell Wall

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Zhang Shiheng¹,Gu Shuang²,Rycroft Piers²,Ruaudel Florence¹,Delolme Frederic³,Robert Xavier⁴,Ballut Lionel⁴,Pickersgill Richard W.²,Shevchik Vladimir E.¹^ORCID

Affiliation:

1. Université Lyon, Université Lyon 1, INSA Lyon, CNRS UMR 5240 Microbiologie Adaptation et Pathogénie, Villeurbanne, France

2. School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom

3. Protein Science Facility, SFR BioSciences, CNRS, UMS3444, Lyon, France

4. Université Lyon, Molecular Microbiology and Structural Biochemistry, UMR5086 CNRS, Lyon, France

Abstract

Gram-negative bacteria have two cell membranes sandwiching a peptidoglycan net that together form a robust protective cell envelope. To translocate effector proteins across this multilayer envelope, bacteria have evolved several specialized secretion systems.

Funder

Centre National de la Recherche Scientifique

Agence Nationale de la Recherche

UKRI | Biotechnology and Biological Sciences Research Council

Cancer Research UK

UKRI | Medical Research Council

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00253-22