Bacterial Type II Secretion System and Its Mitochondrial Counterpart

Author:

Shaliutina-Loginova Anna12,Francetic Olivera3,Doležal Pavel1ORCID

Affiliation:

1. Department of Parasitology, Faculty of Science, BIOCEV, Charles University, Vestec, Czech Republic

2. University of South Bohemia in České Budějovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Research Institute of Fish Culture and Hydrobiology, Vodňany, Czech Republic

3. Institut Pasteur, Université Paris Cité, Biochemistry of Macromolecular Interactions Unit, Department of Structural Biology and Chemistry, CNRS UMR 3528, Paris, France

Abstract

Over the billions of years that bacteria have been around, they have evolved several sophisticated protein secretion nanomachines to deliver toxins, hydrolytic enzymes, and effector proteins into their environments. Of these, the type II secretion system (T2SS) is used by Gram-negative bacteria to export a wide range of folded proteins from the periplasm across the outer membrane.

Funder

Gordon and Betty Moore Foundation and Simons Foundation

Czech Science Foundation

Centre National de la Recherche Scientifique

Agence Nationale de la Recherche

Institut Pasteur

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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