Koala Biovar of Chlamydia pneumoniae Infects Human and Koala Monocytes and Induces Increased Uptake of Lipids In Vitro-Reference-Cited by-同舟云学术

Koala Biovar of Chlamydia pneumoniae Infects Human and Koala Monocytes and Induces Increased Uptake of Lipids In Vitro

Published:2001-12 Issue:12 Volume:69 Page:7894-7897
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Coles Katie A.¹²,Timms Peter³,Smith David W.²⁴

Affiliation:

1. Departments of Public Health1 and

2. Microbiology,2 the University of Western Australia, and

3. Centre for Molecular Biotechnology, School of Life Sciences, Queensland University of Technology, Brisbane,3 Australia

4. Western Australian Centre for Pathology and Medical Research, Sir Charles Gairdner Hospital,4 Perth, and

Abstract

ABSTRACT We examined the ability of the koala biovar of Chlamydia pneumoniae to infect both Hep-2 cells and human monocytes and the effect of infection on the formation of foam cells. The koala biovar produced large inclusions in both human and koala monocytes and in Hep-2 cells. Koala C. pneumoniae induced foam cell formation with and without added low-density lipoprotein, in contrast to TW183, which produced increased foam cell formation only in the presence of low-density lipoprotein.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.69.12.7894-7897.2001

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