Environmental Signals Controlling Production of Hemagglutinin/Protease in Vibrio cholerae-Reference-Cited by-同舟云学术

Environmental Signals Controlling Production of Hemagglutinin/Protease in Vibrio cholerae

Published:2001-10 Issue:10 Volume:69 Page:6549-6553
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Benitez Jorge A.¹,Silva Anisia J.²,Finkelstein Richard A.³

Affiliation:

1. California State University College of Science and Mathematics, Fresno, California 93740-80341;

2. University of California— Davis School of Veterinary Medicine and Veterinary Diagnostic Laboratory, Tulare, California 932742; and

3. Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri 652123

Abstract

ABSTRACT Vibrio cholerae hemagglutinin/protease (Hap) was induced upon nutrient limitation and strongly repressed by glucose. Hap was not produced in a mutant defective in the cyclic AMP (cAMP) receptor protein, suggesting that intracellular cAMP levels mediate Hap expression. No difference was found in Hap production between an rpoS deletion mutant and its isogenic wild-type precursor, indicating that the alternate ς s factor is not essential for Hap expression. Based on these and previous results, we discuss the role of Hap in the pathogenesis of cholera.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.69.10.6549-6553.2001

Reference29 articles.

1. Preliminary assessment of the safety and immunogenicity of a new CTXΦ-negative hemagglutinin/protease-defective El Tor strain as a cholera vaccine candidate;Benitez J. A.;Infect. Immun.,1999

2. Adherence of Vibrio cholerae to cultured differentiated human intestinal cells: an in vitro colonization model

3. Vibrio cholerae soluble hemagglutinin/protease is a metalloenzyme

4. Vibrio cholerae hemagglutinin/protease nicks cholera enterotoxin

5. Luminal glucose concentrations in the gut under normal conditions;Ferraris R. P.;Am. J. Physiol.,1990

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