Sugars Inhibit Expression of the Rugose Phenotype of Vibrio cholerae

Author:

Ali Afsar12,Morris J. Glenn12,Johnson Judith A.132

Affiliation:

1. Department of Epidemiology and Preventive Medicine

2. Veterans Affairs Maryland Health Care System, Baltimore, Maryland

3. Department of Pathology, School of Medicine, University of Maryland Baltimore

Abstract

ABSTRACT Vibrio cholerae can shift to a rugose colony phenotype, reflecting expression of an exopolysaccharide that provides protection against a variety of environmental stresses. Our data indicate that expression of the rugose phenotype is inhibited by a variety of sugars, including sucrose, dextrose, arabinose, fructose, and maltose. Inhibition by sucrose may be one factor in explaining the failure of rugose strains to grow on thiosulfate citrate bile salts sucrose agar, the primary selective medium for V. cholerae .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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