Affiliation:
1. Department of Pharmacy, University of Iceland, Reykjavik, Iceland. kring@rhi.hi.is
Abstract
With reference to the traditional use of Cetraria islandica (Iceland moss) for relief of gastric and duodenal ulcer, plant extracts were screened for in vitro activity against Helicobacter pylori. (+)-Protolichesterinic acid, an aliphatic alpha-methylene-gamma-lactone, was identified as an active component. The MIC range of protolichesterinic acid, in free as well as salt form, was 16 to 64 micrograms/ml.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference15 articles.
1. Polysaccharides in lichens and fungi. II. Antitumour activities on sarcoma-180 of the polysaccharide preparations from Gyrophora esculenta Miyoshi, Cetraria islandica (L.) Ach. var. orientalis Asahina and some other lichens;Fukuoka F.;Gann,1968
2. In vitro susceptibility of antibiotics to Campylobacter pylori;Hardardottir H.;Icel. Med. J.,1990
3. Antitumour activities of some lichen products and their degradation products;Hirayama T.;Yakugaku Zasshi,1980
4. Bacteria in the aetiopathogenesis of gastric cancer: a review;Houben G. M. P.;Scand. J. Gastroenterol.,1995
5. In vitro evaluation of the antimicrobial activity of lichen metabolites as potential preservatives;Ingolfsdottir K.;Antimicrob. Agents Chemother.,1985
Cited by
78 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献