Effects of Some Herbs on the In-vitro Growth of Helicobacter pylori and Their Antioxidant Properties

Abstract

Helicobacter pylori is one of the important causes of chronic gastritis, peptic ulcer, stomach cancer in humans. The importance of these diseases has led to the development of effective drug treatment regimens against them. The basis of this study is the determination of the effects of some medicinal plants on the in-vitro growth of H. pylori and their antimicrobial and antioxidant potential. For this purpose, different parts of 15 plant species were extracted using solvents. Water, ethanol, chloroform, acetone extracts of plants were used and antimicrobial activities of these extracts against both H. pylori and other test microorganisms were investigated using the agar disc diffusion methods. The antioxidant properties of the extracts, which were found to be effective in terms of antimicrobial activity, were determined by the thiocyanate method. As a result, acetone extracts of plants; It was determined that it showed higher antimicrobial activity than water, ethanol, chloroform extracts. The most effective two plants against H. pylori for water, ethanol, chloroform, acetone were Capsella bursa-pastoris, Acorus calamus; Acorus calamus, Achillea millefolium; Acorus calamus, Pimpinella anisum, Acorus calamus, Achillea millefolium, respectively. Acetone extracts of Hypericum perforatum, Rosmarinus officinalis, Achillea millefolium; Acorus calamus, Pimpinella anisum plants were found to have antioxidant properties.