The Complete Genome Sequence of Helicobacter pylori Strain G27

Author:

Baltrus David A.1,Amieva Manuel R.2,Covacci Antonello3,Lowe Todd M.4,Merrell D. Scott5,Ottemann Karen M.6,Stein Markus7,Salama Nina R.8,Guillemin Karen9

Affiliation:

1. Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

2. Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California

3. Cellular Microbiology and Bioinformatics Unit, Novartis Vaccines, 53100 Siena, Italy

4. Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, California

5. Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland

6. Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California

7. Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

8. Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109

9. Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403

Abstract

ABSTRACT Helicobacter pylori is a gram-negative pathogen that colonizes the stomachs of over half the world's population and causes a spectrum of gastric diseases including gastritis, ulcers, and gastric carcinoma. The H. pylori species exhibits unusually high levels of genetic variation between strains. Here we announce the complete genome sequence of H. pylori strain G27, which has been used extensively in H. pylori research.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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