A Novel Auxiliary Agarolytic Pathway Expands Metabolic Versatility in the Agar-Degrading Marine Bacterium Colwellia echini A3 T-Reference-Cited by-同舟云学术

A Novel Auxiliary Agarolytic Pathway Expands Metabolic Versatility in the Agar-Degrading Marine Bacterium Colwellia echini A3 T

Published:2021-05-26 Issue:12 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Pathiraja Duleepa¹,Christiansen Line²,Park Byeonghyeok¹,Schultz-Johansen Mikkel²,Bang Geul³⁴,Stougaard Peter²^ORCID,Choi In-Geol¹^ORCID

Affiliation:

1. Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, South Korea

2. Department of Plant and Environmental Sciences, University of Copenhagen, Copenhagen, Denmark

3. Biomedical Omics Group, Korea Basic Science Institute, Chungbuk, South Korea

4. College of Pharmacy, Korea University, Sejong, South Korea

Abstract

Colwellia echini A3 T is an example of how the gain of gene(s) can lead to the evolutionary expansion of agar-specific polysaccharide utilization loci (PUL). C. echini A3 T encodes two α-agarases in addition to the core β-agarolytic enzymes in its agarolytic PUL. Among the agar-degrading CAZymes identified so far, only a few α-agarases have been biochemically characterized.

Funder

Novo Nordisk Foundation

Danish Council for Independent Research

MOTIE | Korea Institute of Energy Technology Evaluation and Planning

Ministry of Science, Innovation and Higher Education | Danish Agency for Science and Higher Education

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00230-21