Characterization of a Catalase-Negative Methicillin-Resistant Staphylococcus aureus Strain

Author:

Grüner B. M.1,Han S.-R.1,Meyer H.-G.2,Wulf U.1,Bhakdi S.1,Siegel E. K.1

Affiliation:

1. Institute of Medical Microbiology, Johannes Gutenberg University, D-55101 Mainz

2. Department of Health and Infection Prevention, Rheinland-Pfalz Center for Laboratory Investigation, D-56068 Koblenz, Germany

Abstract

ABSTRACT We describe an unusual clinical strain of catalase-negative methicillin-resistant Staphylococcus aureus sensu stricto. Sequence analysis of its catalase gene showed 99.60% identities to the catalase genes of the reference strains. A 5-base deletion, however, led to a shift of the nucleotide reading frame and a loss of the enzymatic activity.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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