Congo red prolongs the incubation period in scrapie-infected hamsters-Reference-Cited by-同舟云学术

Congo red prolongs the incubation period in scrapie-infected hamsters

Published:1995-01 Issue:1 Volume:69 Page:506-508
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Ingrosso L¹,Ladogana A¹,Pocchiari M¹

Affiliation:

1. Laboratory of Virology, Istituto Superiore di Sanità, Rome, Italy.

Abstract

In scrapie-infected cells, Congo red inhibits both the replication of the infectious agent and accumulation of the protease-resistant form of PrP (PrP-res). In this report, we show that Congo red prolongs the incubation periods of hamsters experimentally infected with two different strains of scrapie.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.69.1.506-508.1995

Reference22 articles.

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3. Binding of the protease-sensitive form of prion protein PrP to sulfated glycosaminoglycan and Congo red;Caughey B.;J. Virol.,1994

4. Congo red inhibition of scrapie agent replication;Caughey B.;J. Virol.,1993

5. Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells;Caughey B.;J. Virol.,1989

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