Rescue of vaccinia virus lacking the E3L gene by mutants of E3L-Reference-Cited by-同舟云学术

Rescue of vaccinia virus lacking the E3L gene by mutants of E3L

Published:1995-10 Issue:10 Volume:69 Page:6605-6608
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Chang H W¹,Uribe L H¹,Jacobs B L¹

Affiliation:

1. Department of Microbiology, Arizona State University, Tempe 85287-2701, USA.

Abstract

Vaccinia virus with the E3L gene deleted was able to replicate in RK-13 but not HeLa cells. This host range phenotype could be complemented by an E3L gene expressed transiently from a plasmid. Analysis of mutants of E3L indicates that the ability to complement deletion of E3L correlates with the ability of mutated proteins to bind double-stranded RNA but not with their ability to migrate to the nucleus.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.69.10.6605-6608.1995

Reference22 articles.

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5. Buller M. and B. L. Jacobs. Unpublished observations.

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