Inhibition of Chlorination in Streptomyces aureofaciens by Nitriles and Related Compounds-Reference-Cited by-同舟云学术

Inhibition of Chlorination in Streptomyces aureofaciens by Nitriles and Related Compounds

Published:1973-01 Issue:1 Volume:3 Page:138-140
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Goodman Joseph J.¹,Matrishin Mary¹

Affiliation:

1. Lederle Laboratories, Division of American Cyanamid Co., Pearl River, New York 19065

Abstract

A number of nitriles and cyano compounds inhibited chlorination by Streptomyces aureofaciens . In most cases, this inhibition was enhanced by bromide. Methylene blue and p -amino-propiophenone reversed the inhibition to some extent.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.3.1.138

Reference7 articles.

1. Biosynthesis of Tetracycline I. The halide metabolism of Streptomyces aureofaciens mutants. The preparation and characterization of tetracycline 7-chloro "tetracycline and 7-bromotetracycline;Doershuk A. P.;J. Amer. Chem. Soc.,1959

2. Inhibition of the incorporation of chloride into the tetracycline molecule;Goodman J. J.;J. Bacteriol.,1959

3. Goodman J. J. and M. Matrishin. 1968. Chlorination inhibitors in Streptomyces aureofaciens Nature (London)

4. Competitive inhibition by bromide of incorporation of chloride into the tetracycline molecule;Gourevitch A.;Antibiot. Chemother.,1955

5. The action of 1, 1, 3-tricyano-2-amino-1-propene (U9189) on the thyroid gland of the rat and its effects in thyrotoxicosis;Ingbar S. H.;J. Clin. Endocrinol. Metab.,1961

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