Expression of E8^E2 Is Required for Wart Formation by Mouse Papillomavirus 1 In Vivo-Reference-Cited by-同舟云学术

Expression of E8^E2 Is Required for Wart Formation by Mouse Papillomavirus 1 In Vivo

Published:2021-03-25 Issue:8 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Stubenrauch Frank¹^ORCID,Straub Elke¹,Klein Katrin¹,Kramer Daniela²,Iftner Thomas¹,Wong Margaret³,Roden Richard B. S.³^ORCID

Affiliation:

1. University Hospital Tuebingen, Institute for Medical Virology and Epidemiology of Viral Diseases, Tuebingen, Germany

2. Interfaculty Institute for Biochemistry, University of Tuebingen, Tuebingen, Germany

3. Department of Pathology, The Johns Hopkins University, Baltimore, Maryland, USA

Abstract

HPV encodes an E8^E2 protein which acts as repressors of viral gene expression and genome replication. In cultured normal keratinocytes, E8^E2 is essential for long-term episomal maintenance of HPV 31 (HPV31) genomes, but not for that of HPV16.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01930-20

Reference60 articles.

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5. Construction of a Full Transcription Map of Human Papillomavirus Type 18 during Productive Viral Infection

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1. Deficiency in Ever2 does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1;Journal of Virology;2024-07-23

2. Mus musculus papillomavirus 1 E8^E2 represses expression of late protein E4 in basal-like keratinocytes via NCoR/SMRT-HDAC3 co-repressor complexes to enable wart formation in vivo;mBio;2023-06-29

3. Deregulation of host gene expression by HPV16 E8^E2 knock-out genomes is due to increased productive replication;Virology;2023-04

4. Transcription Properties of Beta-HPV8 and HPV38 Genomes in Human Keratinocytes;Journal of Virology;2022-12-14

5. Functions of Papillomavirus E8^E2 Proteins in Tissue Culture and In Vivo;Viruses;2022-05-02