MtTRC-1, a Novel Transcription Factor, Regulates Cellulase Production via Directly Modulating the Genes Expression of the Mthac-1 and Mtcbh-1 in Myceliophthora thermophila-Reference-Cited by-同舟云学术

MtTRC-1, a Novel Transcription Factor, Regulates Cellulase Production via Directly Modulating the Genes Expression of the Mthac-1 and Mtcbh-1 in Myceliophthora thermophila

Published:2022-10-11 Issue:19 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Li Nan¹²³,Liu Yin¹²³,Liu Defei²³,Liu Dandan²³⁴,Zhang Chenyang²³,Lin Liangcai¹,Zhu Zhijian²³,Li Huiyan¹,Dai Yujie¹,Wang Xingji⁵,Liu Qian²³^ORCID,Tian Chaoguang²³

Affiliation:

1. College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China

2. Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

3. National Technology Innovation Center of Synthetic Biology, Tianjin, China

4. State Key Laboratory of Agrobiotechnology and MOA Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural University, Beijing, China

5. Longda Biotechnology Inc, Shandong, Linyi, China

Abstract

In the present study, we characterized a novel regulator MtTRC-1 in M. thermophila , which regulated cellulase production through direct transcriptional regulation of the Mthac-1 and Mtcbh-1 genes. Our data demonstrated that MtHAC-1 is a key factor for the cellulase secretion capacity of M. thermophila .

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.01263-22

Reference73 articles.